DNA is packaged in the cell as chromatin, which folds into organized domains. Mapping of chromatin contacts in single cells sheds light on the dynamic evolution of these domains between cell divisions. See Article p.61
This is a preview of subscription content, log in via an institution to check access.
Notes
References
Naumova, N. et al. Science 342, 948–953 (2013).
Grand, R. S. et al. Nucleic Acids Res. 42, 12585–12599 (2014).
Dileep, V. et al. Genome Res. 25, 1104–1113 (2015).
Nagano, T. et al. Nature 547, 61–67 (2017).
Denker, A. & de Laat, W. Genes Dev. 30, 1357–1382 (2016).
Rao, S. S. P. et al. Cell 159, 1665–1680 (2014).
Dixon, J. R. et al. Nature 485, 376–380 (2012).
Nora, E. P. et al. Cell 169, 930–944 (2017).
Zuin, J. et al. Proc. Natl Acad. Sci. USA 111, 996–1001 (2014).
Schwarzer, W. et al. Preprint at bioRxiv http://dx.doi.org/10.1101/094185 (2016).
Kubo, N. et al. Preprint at bioRxiv http://dx.doi.org/10.1101/118737 (2017).
Flyamer, I. M. et al. Nature 544, 110–114 (2017).
Stevens, T. J. et al. Nature 544, 59–64 (2017).
Author information
Authors and Affiliations
Corresponding authors
Related links
Related links
Related links in Nature Research
Rights and permissions
About this article
Cite this article
Beagrie, R., Pombo, A. Continuous chromatin changes. Nature 547, 34–35 (2017). https://doi.org/10.1038/547034a
Published:
Issue Date:
DOI: https://doi.org/10.1038/547034a
- Springer Nature Limited
This article is cited by
-
Mercury chloride alters heterochromatin domain organization and nucleolar activity in mouse liver
Histochemistry and Cell Biology (2023)
-
Mustache: multi-scale detection of chromatin loops from Hi-C and Micro-C maps using scale-space representation
Genome Biology (2020)