Skip to main content
Log in

Biomedical science

Protection for anaesthetized mice

  • News & Views
  • Published:

From Nature

View current issue Submit your manuscript

A cognition-enhancing drug called CX546 prevents the neurodegenerative effects of repeated anaesthesia in infant mice by promoting neuronal changes associated with learning and by protecting neurons from death.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Figure 1: Combating ketamine.

Notes

  1. See all news & views

References

  1. Disma, N., Mondardini, M. C., Terrando, N., Absalom, A. R. & Bilotta, F. Paediatr. Anaesth. 26, 6–36 (2016).

    Article  Google Scholar 

  2. Wang, X., Xu, Z. & Miao, C.-H. PLoS ONE 9, e85760 (2014).

    Article  ADS  Google Scholar 

  3. Sun, L. S. et al. J. Am. Med. Assoc. 315, 2312–2320 (2016).

    Article  CAS  Google Scholar 

  4. Davidson, A. J. et al. Lancet 387, 239–250 (2016).

    Article  Google Scholar 

  5. Huang, L., Cichon, J., Ninan, I. & Yang, G. Sci. Transl. Med. 8, 344ra85 (2016).

    Article  Google Scholar 

  6. Brown, E. N., Purdon, P. L. & Van Dort, C. J. Annu. Rev. Neurosci. 34, 601–628 (2011).

    Article  CAS  Google Scholar 

  7. Hayashi, H., Dikkes, P. & Soriano, S. G. Paediatr. Anaesth. 12, 770–774 (2002).

    Article  Google Scholar 

  8. Vutskits, L., Gascon, E., Tassonyi, E. & Kiss, J. Z. Toxicol. Sci. 91, 540–549 (2006).

    Article  CAS  Google Scholar 

  9. Urban, K. R. & Gao, W.-J. Front. Syst. Neurosci. 8, 38 (2014).

    Article  Google Scholar 

  10. Rappaport, B. A., Suresh, S., Hertz, S., Evers, A. S. & Orser, B. A. N. Engl. J. Med. 372, 796–797 (2015).

    Article  CAS  Google Scholar 

  11. http://smarttots.org/wp-content/uploads/2015/08/SmartTots-Case-Statement-2013.pdf

  12. http://smarttots.org/consensus-statement-supplement

  13. Maze, M. Can. J. Anaesth. 63, 212–226 (2016).

    Article  Google Scholar 

  14. van der Schier, R., Roozekrans, M., van Velzen, M., Dahan, A. & Niesters, M. F1000Prime Rep. 6, 79 (2014).

    Article  Google Scholar 

  15. Sackett, D. L. Can. Med. Assoc. J. 167, 363–364 (2002).

    Google Scholar 

  16. Davidson, A. J. et al. Paediatr. Anaesth. 25, 447–452 (2015).

    Article  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Charles Berde.

Related links

Related links

Related links in Nature Research

Neuroscience: Sleep to oblivion

Neuroscience: Unconscious networking

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Cornelissen, L., Berde, C. Protection for anaesthetized mice. Nature 536, 36–37 (2016). https://doi.org/10.1038/536036a

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1038/536036a

  • Springer Nature Limited

Navigation