Skip to main content
SpringerLink
Log in

Synthetic biology

Engineering explored

  • News & Views
  • Published:

From Nature

View current issue Submit your manuscript

Synthetic biology involves the creation of biological systems for new applications by modifying and reassembling biological components. Two views are presented here on the best way to engineer these components so that they reliably generate organisms with desired traits.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Figure 1: Two methods for the synthetic engineering of organisms.

References

  1. Gardner, T. S., Cantor, C. R. & Collins, J. J. Nature 403, 339–342 (2000).

    Article  ADS  CAS  Google Scholar 

  2. Kotula, J. W. et al. Proc. Natl Acad. Sci. USA http://dx.doi.org/10.1073/pnas.1321321111 (2014).

  3. Keasling, J. D. Proc. Am. Phil. Soc. 156, 283–294 (2012).

    Google Scholar 

  4. Sarkar, I., Hauber, I., Hauber, J. & Buchholz, F. Science 316, 1912–1915 (2007).

    Article  ADS  CAS  Google Scholar 

  5. Bastian, S. et al. Metab. Eng. 13, 345–352 (2011).

    Article  CAS  Google Scholar 

  6. Romero, P. A. & Arnold, F. H. Nature Rev. Mol. Cell Biol. 10, 866–876 (2009).

    Article  CAS  Google Scholar 

  7. Trudeau, D. L., Smith, M. A. & Arnold, F. H. Curr. Opin. Chem. Biol. 17, 902–909 (2013).

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Pamela A. Silver and Jeffrey C. Way are at Harvard Medical School and the Wyss Institute for Biologically Inspired Engineering, Boston, Massachusetts 02115, USA.,

    Pamela A. Silver & Jeffrey C. Way

  2. Frances H. Arnold and Joseph T. Meyerowitz are in the Division of Chemistry and Chemical Engineering, California Institute of Technology, Pasadena, California 91125, USA.,

    Frances H. Arnold & Joseph T. Meyerowitz

Authors
  1. Pamela A. Silver
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Jeffrey C. Way
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Frances H. Arnold
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Joseph T. Meyerowitz
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding authors

Correspondence to Pamela A. Silver, Jeffrey C. Way, Frances H. Arnold or Joseph T. Meyerowitz.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Silver, P., Way, J., Arnold, F. et al. Engineering explored. Nature 509, 166–167 (2014). https://doi.org/10.1038/509166a

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1038/509166a

  • Springer Nature Limited

This article is cited by

Search

Navigation