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Not-so-innocent bystanders

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The discovery that most CD4+ T cells killed during HIV infection die through a process known as pyroptosis may provide long-sought explanations for HIV-associated T-cell depletion and inflammation. See Article p.509

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Figure 1: CD4+ T-cell death during HIV-1 infection.

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Authors and Affiliations

  1. Robert F. Siliciano are in the Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland 21218, USA.,

    Andrea L. Cox & Robert F. Siliciano

  2. R.F.S. is also at the Howard Hughes Medical Institute, Baltimore.,

    Robert F. Siliciano

Authors
  1. Andrea L. Cox
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  2. Robert F. Siliciano
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Correspondence to Andrea L. Cox or Robert F. Siliciano.

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Cox, A., Siliciano, R. Not-so-innocent bystanders. Nature 505, 492–493 (2014). https://doi.org/10.1038/505492a

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