Some of the principles underlying how amino-acid sequences determine the three-dimensional structures of proteins have been defined. This has enabled a successful approach to designing protein folds from scratch. See Article p.222
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Höcker, B. A toolbox for protein design. Nature 491, 204–205 (2012). https://doi.org/10.1038/491204a
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DOI: https://doi.org/10.1038/491204a
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