Unlike in other mammals, neuron production in the subventricular region of the human brain becomes depleted in early infancy. This finding calls for a reassessment of the potential role of adult neurogenesis in health and disease. See Letter p.382
References
Ihrie, R. & Álvarez-Buylla, A. Neuron 70, 674–686 (2011).
Kornack, R. D. & Rakic, P. Proc. Natl Acad. Sci. USA 98, 4752–4757 (2001).
Sanai, N. et al. Nature 478, 382–386 (2011).
Weickert, C. S. et al. J. Comp. Neurol. 423, 359–372 (2000).
Sanai, N. et al. Nature 427, 740–744 (2004).
Curtis, M. A. et al. Science 315, 1243–1249 (2007).
Sanai, N., Berger, M. S., Garcia-Verdugo, J. M. & Alvarez-Buylla, A. Science 318, 393 (2007).
Lois, C., García-Verdugo, J.-M. & Alvarez-Buylla, A. Science 271, 978–981 (1996).
Sidman, R. L. & Rakic, P. Brain Res. 62, 1–35 (1973).
Rakic, P. Nature Rev. Neurosci. 10, 724–735 (2009).
Rakic, P. Science 227, 1054–1056 (1985).
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
About this article
Cite this article
Arellano, J., Rakic, P. Gone with the wean. Nature 478, 333–334 (2011). https://doi.org/10.1038/478333a
Published:
Issue Date:
DOI: https://doi.org/10.1038/478333a
- Springer Nature Limited
This article is cited by
-
Intertwined ROS and Metabolic Signaling at the Neuron-Astrocyte Interface
Neurochemical Research (2021)
-
Epigenetic Regulation by Chromatin Activation Mark H3K4me3 in Primate Progenitor Cells within Adult Neurogenic Niche
Scientific Reports (2014)