References
Usher, C. R. Lond. Ophthalmol. Hosp. Rep. 19, 130–236 (1914).
Weil, D, et al. Nature 374, 60–61 ( 1995).
Gibson, F, et al. Nature 374, 62–64 (1995).
Lord, E.M. & Gates, W.H. Am. Nat. 63, 435–442 (1929).
Mburu, P. et al. Genes Funct. 1, 191–203 (1997).
Hasson, T., Heintzelman, M.B., Santos-Sacchi, J., Corey, D.P. & Mooseker, M.S. Proc. Natl. Acad. Sci. USA 92, 9815–9819 (1995).
El-Amraoui, A. et al. Hum. Mol. Genet. 5, 1171–1178 (1996).
Liu, X., Vansant, G., Udovichenko, I.P., Wolfrum, U. & Williams, D.S. Cell Motil. Cytoskel. 37, 240 –252 (1997).
Weston, M.D. et al. Am. J. Hum. Genet. 59, 1074–1083 (1996).
Cheney, R.E. . et al. Cell 75, 13–23 (1993).
Provance, D.W., Wei, M., Ipe, V. & Mercer, J.A. Proc. Natl. Acad. Sci. USA 93, 14554–14558 (1996).
Wu, X.F., Bowers, B., Wei, Q., Kocher, B. & Hammer, J.A. J. Cell Sci. 110, 847–859 (1997).
Acknowledgements
We thank I. Udovichenko and members of L. Goldstein's laboratory for helpful discussions and critical comments. This research was supported by NIH grant EY07042.
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
About this article
Cite this article
Liu, X., Ondek, B. & Williams, D. Mutant myosin VIIa causes defective melanosome distribution in the RPE of shaker-1 mice. Nat Genet 19, 117–118 (1998). https://doi.org/10.1038/470
Issue Date:
DOI: https://doi.org/10.1038/470
- Springer Nature America, Inc.
This article is cited by
-
The genetic and phenotypic landscapes of Usher syndrome: from disease mechanisms to a new classification
Human Genetics (2022)
-
A binding protein regulates myosin-7a dimerization and actin bundle assembly
Nature Communications (2021)
-
Phagosomal and mitochondrial alterations in RPE may contribute to KCNJ13 retinopathy
Scientific Reports (2019)
-
Cone degeneration is triggered by the absence of USH1 proteins but prevented by antioxidant treatments
Scientific Reports (2018)
-
Differentiation of RPE cells from integration-free iPS cells and their cell biological characterization
Stem Cell Research & Therapy (2017)