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Excessive mobility interrupted

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Mobile DNA sequences called L1 contribute to the brain's genetic heterogeneity and may affect neuron function. The protein MeCP2, which is mutated in Rett syndrome, seems to regulate the activity of these genomic elements. See Letter p.443

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Figure 1: Regulation of L1 expression.

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Authors and Affiliations

  1. Lorenz Studer is in the Center for Stem Cell Biology, Developmental Biology Program, Sloan-Kettering Institute for Cancer Research, New York, New York 10065, USA. studerl@mskcc.org,

    Lorenz Studer

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  1. Lorenz Studer
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Studer, L. Excessive mobility interrupted. Nature 468, 383–384 (2010). https://doi.org/10.1038/468383a

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