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On stress and pressure

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The protein angiotensinogen must undergo conformational changes to be cleaved into a precursor of the hormone angiotensin, which increases blood pressure. Oxidative stress seems to mediate this structural alteration. See Letter p.108

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Figure 1: The renin–angiotensin system.

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Authors and Affiliations

  1. Curt D. Sigmund is in the Department of Pharmacology, Roy J. and Lucille A. Carver College of Medicine, University of Iowa, Iowa City, Iowa 52242, USA. curt-sigmund@uiowa.edu,

    Curt D. Sigmund

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  1. Curt D. Sigmund
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Sigmund, C. On stress and pressure. Nature 468, 46–47 (2010). https://doi.org/10.1038/468046a

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