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Conservation in vesicle coats

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Coat proteins of vesicles involved in intracellular membrane trafficking have closely related molecular architectures. The structure of COPI extends known similarities, and strengthens the case for a common evolutionary origin.

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Figure 1: Schematic representation of coat proteins and their assemblies.

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Harrison, S., Kirchhausen, T. Conservation in vesicle coats. Nature 466, 1048–1049 (2010). https://doi.org/10.1038/4661048a

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