Coat proteins of vesicles involved in intracellular membrane trafficking have closely related molecular architectures. The structure of COPI extends known similarities, and strengthens the case for a common evolutionary origin.
References
Lee, C. & Goldberg, J. Cell 142, 123–132 (2010).
Goldstein, J. L., Anderson, R. G. W. & Brown, M. S. Nature 279, 679–685 (1979).
Barlowe, C. et al. Cell 77, 895–907 (1994).
Waters, M. G., Serafini, T. & Rothman, J. E. Nature 349, 248–251 (1991).
Fotin, A. et al. Nature 432, 573–579 (2004).
Fath, S., Mancias, J. D., Bi, X. & Goldberg, J. Cell 129, 1325–1336 (2007).
Stagg, S. M. et al. Cell 134, 474–484 (2008).
Hsia, K.-C. & Hoelz, A. Proc. Natl Acad. Sci. USA 107, 11271–11276 (2010).
Orci, L., Glick, B. S. & Rothman, J. E. Cell 46, 171–184 (1986).
Brohawn, S. G., Leksa, N. C., Spear, E. D., Rajashankar, K. R. & Schwartz, T. U. Science 322, 1369–1373 (2008).
van der Bliek, A. M. & Meyerowitz, E. M. Nature 351, 411–414 (1991).
Serafini, T. et al. Cell 67, 239–253 (1981).
Matsuoka, K. et al. Cell 93, 263–275 (1998).
Goldberg, J. Cell 100, 671–679 (2000).
Chappell, T. G. et al. Cell 45, 3–13 (1986).
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Harrison, S., Kirchhausen, T. Conservation in vesicle coats. Nature 466, 1048–1049 (2010). https://doi.org/10.1038/4661048a
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DOI: https://doi.org/10.1038/4661048a
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