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Gene regulation

Breaking the second genetic code

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Diverse messenger RNAs, and thus proteins, can be generated from a single piece of DNA. A computational approach is helping to uncover complex combinatorial rules by which specific gene instructions are selected.

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Figure 1: Predicting pre-mRNA fate.

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Authors and Affiliations

  1. J. Ramón Tejedor and Juan Valcárcel are at the Centre de Regulació Genòmica and Universitat Pompeu Fabra, Barcelona, Spain. Juan Valcárcel is also at the Institució Catalana de Recerca i Estudis Avançats, Dr. Aiguader 88, 08003 Barcelona, Spain. juan.valcarcel@crg.es,

    J. Ramón Tejedor & Juan Valcárcel

Authors
  1. J. Ramón Tejedor
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  2. Juan Valcárcel
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Tejedor, J., Valcárcel, J. Breaking the second genetic code. Nature 465, 45–46 (2010). https://doi.org/10.1038/465045a

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