To combat intestinal worms, mammals rely on adaptive immune responses mediated by T cells. However, it seems that, initially, innate immune cells mimic T-cell activity, while T cells get ready for action.
References
Anthony, R. M., Rutitzky, L. I., Urban, J. F. Jr, Stadecker, M. J. & Gause, W. C. Nature Rev. Immunol. 7, 975–987 (2007).
Neill, D. R. et al. Nature 464, 1367–1370 (2010).
Saenz, S. A. et al. Nature 464, 1362–1366 (2010).
Moro, K. et al. Nature 463, 540–544 (2009).
Saenz, S. A., Taylor, B. C. & Artis, D. Immunol. Rev. 226, 172–190 (2008).
Trinchieri, G. Semin. Immunol. 7, 83–88 (1995).
Satoh-Takayama, N. et al. Immunity 29, 958–970 (2008).
Wolk, K. et al. Immunity 21, 241–254 (2004).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Eberl, G. Close encounters of the second type. Nature 464, 1285–1286 (2010). https://doi.org/10.1038/4641285a
Published:
Issue Date:
DOI: https://doi.org/10.1038/4641285a
- Springer Nature Limited
This article is cited by
-
What rheumatologists need to know about CRISPR/Cas9
Nature Reviews Rheumatology (2017)
-
Isolation and analysis of group 2 innate lymphoid cells in mice
Nature Protocols (2015)
-
Sustained TL1A expression modulates effector and regulatory T-cell responses and drives intestinal goblet cell hyperplasia
Mucosal Immunology (2011)
-
RORγt+ innate lymphoid cells regulate intestinal homeostasis by integrating negative signals from the symbiotic microbiota
Nature Immunology (2011)
-
The innate side of TOX
Nature Immunology (2010)