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Cell biology

Stability in times of stress

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Damaged lysosomes, the principal degradative organelles, can kill a cell. A stress-induced protein controls lysosome stability, providing a potential target to treat lysosome-related diseases and cancer.

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Figure 1: A protein–lipid interaction stabilizes lysosome membranes.

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Authors and Affiliations

  1. Ibolya Horváth and László Vígh are at the Institute of Biochemistry, Biological Research Centre of the Hungarian Academy of Sciences, Szeged H-6726, Hungary. vigh@brc.hu ,

    Ibolya Horváth & László Vígh

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  1. Ibolya Horváth
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  2. László Vígh
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Horváth, I., Vígh, L. Stability in times of stress. Nature 463, 436–438 (2010). https://doi.org/10.1038/463436a

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