Immune cells cross the inflamed blood–brain barrier. But it's unclear how brain inflammation begins before immune-cell entry. Studies of a model of multiple sclerosis start to solve this 'chicken and egg' conundrum.
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Ransohoff, R. In the beginning. Nature 462, 41–42 (2009). https://doi.org/10.1038/462041a
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DOI: https://doi.org/10.1038/462041a
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