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Microscopy

Light from the dark

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Fluorescence microscopy is the most popular way to image biomolecules, but it leaves many of them in the dark. Non-fluorescent, light-absorbing molecules can now be viewed by a method that turns them into mini-lasers.

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Figure 1: Imaging non-fluorescent molecules using stimulated emission.

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Hell, S., Rittweger, E. Light from the dark. Nature 461, 1069–1070 (2009). https://doi.org/10.1038/4611069a

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