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Molecular biology

The Bloom's complex mousetrap

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Genomic instability often underlies cancer. Analyses of proteins implicated in a cancer-predisposing condition called Bloom's syndrome illustrate the intricacies of protein interactions that ensure genomic stability.

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Figure 1: Double Holliday junctions caught in the mousetrap.

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Authors and Affiliations

  1. Robert M. Brosh Jr is in the Laboratory of Molecular Gerontology, National Institute on Aging, National Institutes of Health, NIH Biomedical Research Center, Baltimore, Maryland 21224, USA. broshr@mail.nih.gov ,

    Robert M. Brosh Jr

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  1. Robert M. Brosh Jr
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Brosh, R. The Bloom's complex mousetrap. Nature 456, 453–454 (2008). https://doi.org/10.1038/456453a

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