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Myoglobin's new clothes

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Nitric oxide generated from the nitrite ion limits the tissue damage caused by restricted blood flow. Gene knockout experiments in mice now reveal that myoglobin is the mediator of this effect.

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Figure 1: Myoglobin as a reductase and an oxygenase.

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Authors and Affiliations

  1. Andrew Cossins and Michael Berenbrink are in the School of Biological Sciences, University of Liverpool, Liverpool L69 7ZB, UK. cossins@liverpool.ac.uk ,

    Andrew Cossins & Michael Berenbrink

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  1. Andrew Cossins
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  2. Michael Berenbrink
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Cossins, A., Berenbrink, M. Myoglobin's new clothes. Nature 454, 416–417 (2008). https://doi.org/10.1038/454416a

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