Given the lung's thousands of branching airways, its development might be expected to be a highly complex process. Yet a surprisingly simple picture now emerges of when, where and in what order these branches form.
This is a preview of subscription content, log in via an institution to check access.
References
Metzger, R. J., Klein, O. D., Martin, G. R. & Krasnow, M. A. Nature 453, 745–750 (2008).
Maillieux, A. A. et al. Mech. Dev. 102, 81–94 (2001).
Unbekandt, M. et al. Mech. Dev. 125, 314–324 (2008).
Affolter, M. et al. Dev. Cell 4, 11–18 (2003).
Tefft, D. J. et al. Curr. Biol. 9, 219–222 (1999).
Warburton, D. et al. Pediatr. Res. 57, 26R–37R (2005).
Cardoso, W. V. & Lü, J. Development 133, 1611–1624 (2006).
De Robertis, E. M. Cell 132, 185–195 (2008).
Centanin, L. et al. Dev. Cell 14, 547–558 (2008).
Del Moral, P.-M. et al. Dev. Biol. 290, 177–188 (2006).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Warburton, D. Order in the lung. Nature 453, 733–734 (2008). https://doi.org/10.1038/453733a
Published:
Issue Date:
DOI: https://doi.org/10.1038/453733a
- Springer Nature Limited
This article is cited by
-
Automatic and adaptive heterogeneous refractive index compensation for light-sheet microscopy
Nature Communications (2017)
-
The developing story of Sprouty and cancer
Cancer and Metastasis Reviews (2014)
-
Differential expression of coxsackievirus and adenovirus receptor on alveolar epithelial cells between fetal and adult mice determines their different susceptibility to coxsackievirus B infection
Archives of Virology (2012)