Skip to main content
Log in

Epigenetics

Perceptive enzymes

  • News & Views
  • Published:

From Nature

View current issue Submit your manuscript

Adding methyl groups to DNA is a way of regulating some genes and genomic sequences. Structural analysis reveals that the enzyme complex that mediates this process shows unexpected sequence specificity.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Figure 1: Covert signals.

References

  1. Edwards, C. A. & Ferguson-Smith, A. C. Curr. Opin. Cell Biol. 19, 281–289 (2007).

    Article  CAS  Google Scholar 

  2. Jia, D., Jurkowska, R. Z., Zhang, X., Jeltsch, A. & Cheng, X. Nature 449, 248–251 (2007).

    Article  ADS  CAS  Google Scholar 

  3. Fazzari, M. J. & Greally, J. M. Nature Rev. Genet. 5, 446–455 (2004).

    Article  CAS  Google Scholar 

  4. Bourc'his, D., Xu, G.-L., Lin, C.-S., Bollman, B. & Bestor, T. H. Science 294, 2536–2539 (2001).

    Article  ADS  CAS  Google Scholar 

  5. Bourc'his, D. & Bestor, T. H. Nature 431, 96–99 (2004).

    Article  ADS  CAS  Google Scholar 

  6. Kaneda, M. et al. Nature 429, 900–903 (2004).

    Article  ADS  CAS  Google Scholar 

  7. Gowher, H. & Jeltsch, A. J. Mol. Biol. 309, 1201–1208 (2001).

    Article  CAS  Google Scholar 

  8. Ooi, S. K. T. et al. Nature 448, 714–717 (2007).

    Article  ADS  CAS  Google Scholar 

  9. Kent, W. J. et al. Genome Res. 12, 996–1006 (2002).

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

Ferguson-Smith, A., Greally, J. Perceptive enzymes. Nature 449, 148–149 (2007). https://doi.org/10.1038/449148a

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1038/449148a

  • Springer Nature Limited

This article is cited by

Navigation