Skip to main content
Log in

Neuroscience

Obsessed with grooming

  • News & Views
  • Published:

From Nature

View current issue Submit your manuscript

Roughly 2% of humans suffer from obsessive compulsive disorder, but a lack of animal models has impeded research into this condition. Could a genetically engineered mouse model provide an exciting lead?

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

References

  1. Chamberlain, S. R., Menzies, L., Sahakian, B. J. & Fineberg, N. A. Am. J. Psychiatry 164, 568–574 (2007).

    Article  Google Scholar 

  2. Welch, J. M. et al. Nature 448, 894–900 (2007).

    Article  ADS  CAS  Google Scholar 

  3. Hollander, E., Kim, S., Khanna, S. & Pallanti, S. CNS Spectr. 12 (suppl. 3), 5–13 (2007).

    Article  Google Scholar 

  4. Merikangas, K. R. & Risch, N. Am. J. Psychiatry 160, 625–635 (2003).

    Article  Google Scholar 

  5. Robinson, D. et al. Arch. Gen. Psychiatry 52, 393–398 (1995).

    Article  CAS  Google Scholar 

  6. Pujol, J. et al. Arch. Gen. Psychiatry 61, 720–730 (2004).

    Article  Google Scholar 

  7. Bloch, M. H., Leckman, J. F., Zhu, H. & Peterson, B. S. Neurology 65, 1253–1258 (2005).

    Article  Google Scholar 

  8. Remijnse, P. L. et al. Arch. Gen. Psychiatry 63, 1225–1236 (2006).

    Article  Google Scholar 

  9. Bice, P. J. et al. Behav. Genet. 36, 248–260 (2006).

    Article  Google Scholar 

  10. Shahbazian, M. et al. Neuron 35, 243–254 (2002).

    Article  CAS  Google Scholar 

  11. Clapcote, S. J. et al. Neuron 54, 387–402 (2007).

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

Hyman, S. Obsessed with grooming. Nature 448, 871–872 (2007). https://doi.org/10.1038/448871a

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1038/448871a

  • Springer Nature Limited

Navigation