T helper-17 cells, which are involved in immune responses, arise from a pool of precursor cells. It emerges that their differentiation is partly mediated by the IL-21 protein, which originates from the helper cells themselves.
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Palmer, M., Weaver, C. Narcissistic helpers. Nature 448, 416–417 (2007). https://doi.org/10.1038/448416a
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DOI: https://doi.org/10.1038/448416a
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