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Stem cells

Good, bad and reformable

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The ability of stem cells to continuously supply vast numbers of cells is magnificent, but it can be devastating if it runs amok, as in some tumours. So what makes a normal stem cell turn bad, and can it be redeemed?

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Figure 1: PTEN regulates signal transduction and cancer development.

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Authors and Affiliations

  1. the Center for Regenerative Medicine, Massachusetts General Hospital, Harvard Stem Cell Institute, 185 Cambridge Street, Boston, 02114, Massachusetts, USA

    Viktor Janzen & David T. Scadden

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  1. Viktor Janzen
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  2. David T. Scadden
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Janzen, V., Scadden, D. Good, bad and reformable. Nature 441, 418–419 (2006). https://doi.org/10.1038/441418b

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