Proteins are not the only regulators of metabolite synthesis — some RNA molecules do it too. These RNAs lack chemical diversity, so how do we explain the variety of their respective substrates?
References
Serganov, A., Polonskaia, A., Phan, A. T., Breaker, R. R. & Patel, D. J. Nature 441, 1167–1171 (2006).
Montange, R. K. & Batey, R. T. Nature 441, 1172–1175 (2006).
Mandal, M. et al. Cell 113, 577–586 (2003).
Sudarsan, N. et al. RNA 9, 644–647 (2003).
Serganov, A. et al. Chem. Biol. 11, 1729–1741 (2004).
Batey, R. T., Gilbert, S. D. & Montange, R. K. Nature 432, 411–415 (2004).
Thore, S., Leinbundgut, M. & Ban, N. Science 312, 1208–1211 (2006).
Cate, J. H., Hanna, R. L. & Doudna, J. A. Nature Struct. Biol. 4, 553–558 (1997).
Winkler, W. C. Curr. Opin. Chem. Biol. 9, 594–602 (2005).
Jenison, R. D. et al. Science 263, 1425–1429 (1994).
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Reichow, S., Varani, G. RNA switches function. Nature 441, 1054–1055 (2006). https://doi.org/10.1038/4411054a
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DOI: https://doi.org/10.1038/4411054a
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