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RNA switches function

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Proteins are not the only regulators of metabolite synthesis — some RNA molecules do it too. These RNAs lack chemical diversity, so how do we explain the variety of their respective substrates?

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Figure 1: Gene regulation by riboswitches.

References

  1. Serganov, A., Polonskaia, A., Phan, A. T., Breaker, R. R. & Patel, D. J. Nature 441, 1167–1171 (2006).

    Article  ADS  CAS  Google Scholar 

  2. Montange, R. K. & Batey, R. T. Nature 441, 1172–1175 (2006).

    Article  ADS  CAS  Google Scholar 

  3. Mandal, M. et al. Cell 113, 577–586 (2003).

    Article  CAS  Google Scholar 

  4. Sudarsan, N. et al. RNA 9, 644–647 (2003).

    Article  CAS  Google Scholar 

  5. Serganov, A. et al. Chem. Biol. 11, 1729–1741 (2004).

    Article  CAS  Google Scholar 

  6. Batey, R. T., Gilbert, S. D. & Montange, R. K. Nature 432, 411–415 (2004).

    Article  ADS  CAS  Google Scholar 

  7. Thore, S., Leinbundgut, M. & Ban, N. Science 312, 1208–1211 (2006).

    Article  ADS  CAS  Google Scholar 

  8. Cate, J. H., Hanna, R. L. & Doudna, J. A. Nature Struct. Biol. 4, 553–558 (1997).

    Article  CAS  Google Scholar 

  9. Winkler, W. C. Curr. Opin. Chem. Biol. 9, 594–602 (2005).

    Article  CAS  Google Scholar 

  10. Jenison, R. D. et al. Science 263, 1425–1429 (1994).

    Article  ADS  CAS  Google Scholar 

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Reichow, S., Varani, G. RNA switches function. Nature 441, 1054–1055 (2006). https://doi.org/10.1038/4411054a

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