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Developmental biology

A message to the back side

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Vertebrate embryos from fish to mammals seem to use different routes to work out which way is up and which side is front. Yet a novel system involved in defining the dorsal side of fish might be conserved in mammals.

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Figure 1: Maternal mRNA that encodes Nodal moves to the dorsal side.

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Driever, W. A message to the back side. Nature 438, 926–927 (2005). https://doi.org/10.1038/438926b

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