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The RNAi revolution

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The term RNAi — short for RNA interference — crops up again and again in biology research these days. This is in part because of its power as a laboratory tool, and in part because it is a widespread natural phenomenon.

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Figure 1
Figure 2: Short interfering RNAs — post-transcriptional gene silencing.
Figure 3: MicroRNAs — translational silencing.

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Authors and Affiliations

  1. Center for Cancer Research,

    Carl D. Novina & Phillip A. Sharp

  2. Department of Biology and the McGovern Institute, Massachusetts Institute of Technology, Cambridge, 02139, Massachusetts, USA

    Carl D. Novina & Phillip A. Sharp

Authors
  1. Carl D. Novina
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  2. Phillip A. Sharp
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Novina, C., Sharp, P. The RNAi revolution. Nature 430, 161–164 (2004). https://doi.org/10.1038/430161a

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