For years, a unicellular creature called Giardia has occupied a special place in biology because it was thought to lack mitochondria. But it does have them — though tiny, they pack a surprising anaerobic punch.
References
Martin, W., Hoffmeister, M., Rotte, C. & Henze, K. Biol. Chem. 382, 1521–1539 (2001).
Sogin, M., Gunderson, J., Elwood, H., Alonso, R. & Peattie, D. Science 243, 75–77 (1989).
Wheelis, M. L., Kandler, O. & Woese, C. R. Proc. Natl Acad. Sci. USA 89, 2930–2934 (1992).
Tovar, J. et al. Nature 426, 172–176 (2003).
Müller, M. in Molecular Medical Parasitology (ed. Marr, J.) 125–139 (Academic, London, 2003).
Lloyd, D. & Harris, J. C. Trends Microbiol. 10, 122–127 (2002).
Lloyd, D., Ralphs, J. R. & Harris, J. C. Microbiology 148, 727–733 (2002).
Cammack, R., Horner, D. S., van der Giezen, M., Kulda, J. & Lloyd, D. in Biochemistry and Physiology of Anaerobic Bacteria (eds Ljungdahl, L. G., Adams, M. W., Barton, L. L., Ferry, J. G. & Johnson, M.) 113–127 (Springer, New York, 2003).
Embley, T. M. et al. IUBMB Life 55, 387–395 (2003).
Lill, R. & Kispal, G. Trends Biochem. Sci. 25, 352–355 (2000).
Gray, M. W., Burger, G. & Lang, B. F. Science 283, 1476–1481 (1999).
Tielens, A. G. M., Rotte, C., van Hellemond, J. & Martin, W. Trends Biochem. Sci. 27, 564–572 (2002).
Tovar, J., Fischer, A. & Clark, C. G. Mol. Microbiol. 32, 1013–1021 (1999).
Williams, B. A., Hirt, R. P., Lucocq, J. M. & Embley, T. M. Nature 418, 865–869 (2002).
Katinka, M. D. et al. Nature 414, 450–453 (2001).
Lloyd, D. et al. Microbiology 148, 1349–1354 (2002).
Knoll, A. H. Life on a Young Planet: The First Three Billion Years of Evolution on Earth 122–160 (Princeton Univ. Press, 2003).
Theissen, U. et al. Mol. Biol. Evol. 20, 1564–1574 (2003).
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Henze, K., Martin, W. Essence of mitochondria. Nature 426, 127–128 (2003). https://doi.org/10.1038/426127a
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DOI: https://doi.org/10.1038/426127a
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