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Prion diseases

A nucleic-acid accomplice?

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Prion proteins that trigger a cascade of protein misfolding in the brain are suspected of being the sole transmissible cause of some brain-destroying diseases. But nucleic acids could be their partner in crime.

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Caughey, B., Kocisko, D. A nucleic-acid accomplice?. Nature 425, 673–674 (2003). https://doi.org/10.1038/425673a

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