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The hippo hypothesis

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The perfection of a fly's eye and the chaotic nature of tumours provide eloquent examples of the need to coordinate cell death and proliferation. The intricacies of the underlying mechanism are now being uncovered.

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Figure 1: Eyes right, and wrong.

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Authors and Affiliations

  1. Departments of Physiology and Biochemistry, Howard Hughes Medical Institute, University of California, San Francisco, 94143-0725, California, USA

    Michael E. Rothenberg & Yuh-Nung Jan

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  1. Michael E. Rothenberg
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  2. Yuh-Nung Jan
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Correspondence to Yuh-Nung Jan.

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Rothenberg, M., Jan, YN. The hippo hypothesis. Nature 425, 469–470 (2003). https://doi.org/10.1038/425469a

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