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Immunology

Dangerous liaisons

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Alerting the immune system to invading microorganisms is essential for effective immunity. Uric acid released by damaged cells is a danger signal that is able to notify immune cells of microbial attack.

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Figure 1: Strangers and danger.

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Authors and Affiliations

  1. Division of Immunology, Walter and Eliza Hall Institute of Medical Research, Parkville, 3050, Victoria, Australia

    William R. Heath

  2. Department of Microbiology and Immunology, University of Melbourne, Parkville, 3010, Victoria, Australia

    Francis R. Carbone

Authors
  1. William R. Heath
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  2. Francis R. Carbone
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Heath, W., Carbone, F. Dangerous liaisons. Nature 425, 460–461 (2003). https://doi.org/10.1038/425460a

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