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Genomic imprinting

Piece of cake

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Knocking out a minor form of the Igf2 messenger RNA from the placenta in mice has surprisingly strong effects on nutrient transport to the fetus. This has implications for the theory of maternal–paternal genetic conflict.

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Figure 1: Cross-section of the mouse placenta.

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Correspondence to Benjamin Tycko or Argiris Efstratiadis.

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Tycko, B., Efstratiadis, A. Piece of cake. Nature 417, 913–914 (2002). https://doi.org/10.1038/417913a

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