In order to move, cells need to push out protrusions known as lamellipods. These can vary greatly in their shapes, dynamics and contributions to motility, depending on their underlying molecular architecture.
References
Bear, J. E. et al. Cell 109, 509–521 (2002).
Renfranz, P. J. & Beckerle, M. C. Curr. Opin. Cell Biol. 14, 88–103 (2002).
Reinhard, M., Jarchau, T. & Walter, U. Trends Biochem. Sci. 26, 243–249 (2001).
Rottner, K., Behrendt, B., Small, J. V. & Wehland, J. Nature Cell Biol. 1, 321–322 (1999).
Bear, J. E. et al. Cell 101, 717–728 (2000).
Amann, K. J. & Pollard, T. D. Proc. Natl Acad. Sci. USA 98, 15009–15013 (2001).
Resch, G. P., Goldie, K. N., Krebs, A., Hoenger, A. & Small, J. V. J. Cell Sci. 115, 1877–1882 (2002).
Resch, G. P., Goldie, K. N., Hoenger, A. & Small, J. V. J. Struct. Biol. (in the press).
Ichetovkin, I., Grant, W. & Condeelis, J. Curr. Biol. 12, 79–84 (2002).
Pantaloni, D., Boujemaa, R., Didry, D., Gounon, P. & Carlier, M. F. Nature Cell Biol. 2, 385–391 (2000).
Huang, M. et al. Curr. Biol. 9, 979–982 (1999).
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Machesky, L. Sharks' teeth and dunes. Nature 417, 495–497 (2002). https://doi.org/10.1038/417494a
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DOI: https://doi.org/10.1038/417494a
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