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Stem cells

Cell fusion causes confusion

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'Transdifferentiation' is a poorly understood process invoked to explain how tissue-specific adult stem cells can generate cells of other tissues. New results challenge its existence.

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Figure 1: Can adult stem cells transdifferentiate into other cell types?

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Authors and Affiliations

  1. Laboratory of Genetics, The Salk Institute, 10010 North Torrey Pines Road, La Jolla, 92037, California, USA

    Andrew E. Wurmser & Fred H. Gage

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  1. Andrew E. Wurmser
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  2. Fred H. Gage
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Correspondence to Fred H. Gage.

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Wurmser, A., Gage, F. Cell fusion causes confusion. Nature 416, 485–487 (2002). https://doi.org/10.1038/416485a

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