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Short cut to disease genes

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There are thousands of inherited human diseases. For the most part, the genes that are mutated in these diseases are unknown. But a new approach could save time and effort in identifying the genes responsible.

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Figure 1: Serial analysis of gene expression (SAGE) in the retina, as carried out by Cepko and colleagues1.

References

  1. Blackshaw, S., Fraioli, R. E., Furukawa, T. & Cepko, C. L. Cell 107, 579–589 (2001).

    Article  CAS  Google Scholar 

  2. Cepko, C. L., Austin, C. P., Yang, X., Alexiades, M. & Ezzeddine, D. Proc. Natl Acad. Sci. USA 93, 589–595 (1996).

    Article  ADS  CAS  Google Scholar 

  3. RetNet Retinal Information Network; http://www.sph.uth.tmc.edu/retnet/

  4. Velculescu, V. E., Zhang, L., Vogelstein, B. & Kinzler, K. W. Science 270, 484–487 (1995).

    Article  ADS  CAS  Google Scholar 

  5. Velculescu, V. E., Vogelstein, B. & Kinzler, K. W. Trends Genet. 16, 423–425 (2000).

    Article  CAS  Google Scholar 

  6. Velculescu, V. E. et al. Nature Genet. 23, 387–388 (1999).

    Article  CAS  Google Scholar 

  7. Moreno, J. C. et al. Genomics 75, 70–76 (2001).

    Article  CAS  Google Scholar 

  8. Wright, A. F. & Hastie, N. Genome Biol. 2, 2007.1–2007.8(2001).

    Google Scholar 

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Correspondence to Alan F. Wright.

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Wright, A., Van Heyningen, V. Short cut to disease genes. Nature 414, 705–706 (2001). https://doi.org/10.1038/414705a

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