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Cell-cycle control and its watchman

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The mammalian cell cycle is controlled by systems that monitor the cell's health and act through the tumour-suppressor p53 and its effector, p21. Therapeutic intervention can restore order to tumour cells lacking p53.

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Authors and Affiliations

  1. MIT Center for Cancer Research, Department of Biology, MIT,

    Tyler Jacks

  2. the Howard Hughes Medical Institute,

    Tyler Jacks

  3. The Department of Biology, MIT,

    Robert A. Weinberg

  4. the Whitehead Institute, Cambridge, Massachusetts, 02139, USA

    Robert A. Weinberg

Authors
  1. Tyler Jacks
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  2. Robert A. Weinberg
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Jacks, T., Weinberg, R. Cell-cycle control and its watchman. Nature 381, 643–644 (1996). https://doi.org/10.1038/381643a0

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