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Fast sequencing of oligosaccharides using arrays of enzymes

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A new strategy for sequencing oligosaccharides involves generating fragments at 'stop points' along the molecule using enzyme matrices.

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References

  1. Seminars in Cell Biology Vol. 2, No. 5 (eds Dwek, R. A. & Parekh, R. B.) (Saunders, London, 1992).

  2. Kobata, A. Analyt. Biochem. 100, 1–14 (1979).

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  3. Edge, C. J. et al. Proc. natn. Acad. Sci. U.S.A. 89, 6338–6342 (1992).

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Author notes

  1. Christopher Edge, Raj Parekh, Thomas Rademacher, Mark Wormald and Raymond Dwek: which is supported by Monsanto Company

Authors and Affiliations

  1. members of the Glycobiology Institute, Oxford University, South Parks Road, Oxford, 0X13QU, UK

    Christopher Edge, Raj Parekh, Thomas Rademacher, Mark Wormald & Raymond Dwek

  2. vice-president and director of research at Oxford GlycoSystems, Unit 4, Blacklands Way, Hitching Court, Abingdon Business Park, Abingdon, Oxon, 0X14 1RG, UK

    Raj Parekh

Authors
  1. Christopher Edge
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  2. Raj Parekh
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  3. Thomas Rademacher
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  4. Mark Wormald
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  5. Raymond Dwek
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Edge, C., Parekh, R., Rademacher, T. et al. Fast sequencing of oligosaccharides using arrays of enzymes. Nature 358, 693–694 (1992). https://doi.org/10.1038/358693a0

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