Huntington's disease results from defects in the huntingtin protein, but the exact mechanism has been unclear. Researchers now have a better idea, and the knowledge has proved beneficial — for flies at least.
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References
Steffan, J. S. et al. Nature 413, 739–743 (2001).
Kazantsev, A., Preisinger, E., Dranovsky, A., Goldgaber, D. & Housman, D. Proc. Natl Acad. Sci. USA 96, 11404–11409 (1999).
Steffan, J. S. et al. Proc. Natl Acad. Sci. USA 97, 6763–6768 (2000).
Nucifora, F. C. Jr et al. Science 291, 2423–2428 (2001).
McCampbell, A. et al. Hum. Mol. Genet. 9, 2197–2202 (2000).
Luthi-Carter, R. et al. Hum. Mol. Genet. 9, 1259–1271 (2000).
Nakamura, K. et al. Hum. Mol. Genet. 10, 1441–1448 (2001).
Murata, T. et al. Hum. Mol. Genet. 10, 1071–1076 (2001).
Scherzinger, E. et al. Proc. Natl Acad. Sci. USA 96, 4604–4609 (1999).
Marks, P. A., Rifkind, R. A., Richon, V. M. & Breslow, R. Clin. Cancer Res. 7, 759–760 (2001).
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Bates, G. Exploiting expression. Nature 413, 691–693 (2001). https://doi.org/10.1038/35099656
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DOI: https://doi.org/10.1038/35099656
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