When tissues need more oxygen, they release molecules that encourage blood vessels to grow. The discovery of the first such molecule that is specific to one type of tissue has implications for cancer and heart failure.
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Carmeliet, P. Creating unique blood vessels. Nature 412, 868–869 (2001). https://doi.org/10.1038/35091178
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DOI: https://doi.org/10.1038/35091178
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