RNA silencing allows cells to block invading viruses or mobile DNAs. An RNA-cleaving enzyme involved in the first step of silencing has now been identified.
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References
Bernstein, E., Caudy, A. A., Hammond, S. M. & Hannon, G. J. Nature 409, 363–366 ( 2001).
Plasterk, R. H. A. & Ketting, R. F. Curr. Opin. Genet. Dev. 10, 562–567 (2000).
Mourrain, P. et al. Cell 101, 533–542 (2000).
Fire, A. et al. Nature 391, 806–811 (1998).
Zamore, P. D., Tuschl, T., Sharp, P. A. & Bartel, D. P. Cell 101, 25–33 (2000).
Hammond, S. M., Bernstein, E., Beach, D. & Hannon, G. Nature 404, 293–296 (2000).
Cerutti, L., Mian, N. & Bateman, A. Trends Biochem. Sci. 25, 481– 482 (2000).
Fagard, M., Boutet, S., Morel, J.-B, Bellini, C. & Vaucheret, H. Proc. Natl Acad. Sci. USA 97, 11650–11654 (2000).
Tabara, H. et al. Cell 99, 123–132 (1999).
Catalanotto, C., Azzalin, G., Macino, G. & Cogoni, C. Nature 404, 245 (2000).
Jacobsen, S. E., Running, M. P. & Meyerowitz, E. M. Development 126, 5231– 5243 (1999).
Smardon, A. et al. Curr. Biol. 10, 169– 178 (2000).
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Baulcombe, D. Diced defence. Nature 409, 295–296 (2001). https://doi.org/10.1038/35053256
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DOI: https://doi.org/10.1038/35053256
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