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Osteoimmunology

Bone versus immune system

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A molecule on activated T cells triggers bone loss by switching on bone-resorbing cells. Fortunately, it seems that this mechanism is kept in check by another molecule, secreted by the T cells.

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Figure 1: The interface between the immune system and bones.

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Authors and Affiliations

  1. Tri-Institutional MD–PhD Program,

    Joseph R. Arron & Yongwon Choi

  2. Howard Hughes Medical Institute, Laboratory of Immunology, The Rockefeller University, New York , 10021, New York, USA

    Joseph R. Arron & Yongwon Choi

Authors
  1. Joseph R. Arron
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  2. Yongwon Choi
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Correspondence to Joseph R. Arron or Yongwon Choi.

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Arron, J., Choi, Y. Bone versus immune system. Nature 408, 535–536 (2000). https://doi.org/10.1038/35046196

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