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Long-term depression with a flash

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Abstract

The site of expression of hippocampal synaptic plasticity has been hotly debated. A new study demonstrates that postsynaptic neurons alone can express long-term depression.

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Figure 1: A hippocampal CA1 pyramidal cell is bathed in caged glutamate.

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Author information

Authors and Affiliations

  1. Dept. of Psychiatry, University of California, San Francisco, 94143, California, USA

    Robert Malenka

  2. Dept. of Physiology, University of California, San Francisco, 94143, California, USA

    Robert Malenka

  3. Dept. of Cellular and Molecular Pharmacology, University of California, San Francisco, 94143, California, USA

    Roger Nicoll

  4. Dept. of Physiology, University of California, San Francisco, 94143, California, USA

    Roger Nicoll

Authors
  1. Robert Malenka
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  2. Roger Nicoll
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Corresponding authors

Correspondence to Robert Malenka or Roger Nicoll.

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Malenka, R., Nicoll, R. Long-term depression with a flash. Nat Neurosci 1, 89–90 (1998). https://doi.org/10.1038/333

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