Abstract
A putative growth hormone receptor from rabbit liver and the growth hormone binding protein from rabbit serum have the same ammo-terminal amino-acid sequence, indicating that the binding protein corresponds to the extracellular hormone-binding domain of the liver receptor. The complete amino-acid sequences derived from complementary DNA clones encoding the putative human and rabbit growth hormone receptors are not similar to other known proteins, demonstrating a new class of transmembrane receptors.
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Leung, D., Spencer, S., Cachianes, G. et al. Growth hormone receptor and serum binding protein: purification, cloning and expression. Nature 330, 537–543 (1987). https://doi.org/10.1038/330537a0
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DOI: https://doi.org/10.1038/330537a0
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