Abstract
Examination of 10 chromosomal rearrangements induced by foldback transposable elements in Drosophila demonstrates that sequences located between two closely linked elements are frequently deleted. Rearrangements and recombination events occurring within or adjacent to a foldback element are also observed. The type and frequency of rearrangement generated depend on element structure and the organization of flanking DNA.
This is a preview of subscription content, log in via an institution to check access.
Similar content being viewed by others
References
Shapiro, J. A. (ed.) Mobile Genetic Elements (Academic, New York, 1983).
Levis, R., Collins, M. & Rubin, G. M. Cell 30, 551–565 (1982).
Paro, R., Goldberg, M. L. & Gehring, W. J. EMBO J. 2, 853–860 (1983).
Potter, S. S., Truett, M. A., Phillips, M. & Maher, A. Cell 20, 639–647 (1980).
Truett, M. A., Jones, R. S. & Potter, S. S. Cell 24, 753–763 (1982).
Potter, S. S. Nature 297, 201–204 (1982).
Green, M. M. Genetics 56, 467–482 (1967).
Karess, R. E. & Rubin, G. M. Cell 30, 63–69 (1982).
Collins, M. & Rubin, G. M. Cell 30, 71–79 (1982).
Collins, M. & Rubin, G. M. Nature 303, 259–260 (1983).
Judd, B. H., Shen, M. W. & Kaufman, T. C. Genetics 71, 139–156 (1972).
Levis, R., Bingham, P. M. & Rubin, G. M. Proc. natn. Acad. Sci. U.S.A. 79, 564–568 (1982).
Levis, R. & Rubin, G. M. Cell 30, 543–550 (1982).
Kleckner, N. A. Rev. Genet. 15, 341–404 (1981).
Liebman, S., Shalit, P. & Picologlou, S. Cell 26, 401–409 (1981).
Stiles, J. I., Freidman, L. R., Helms, C., Consaul, S. & Sherman, F. J. molec. Biol. 148, 331–346 (1981).
Green, M. M. Genetics 61, 429–441 (1969).
O'Hare, K. & Rubin, G. M. Cell 34, 25–35 (1983).
Engels, W. A. Rev. Genet. 17, 315–344 (1983).
O'Hare, K., Levis, R. & Rubin, G. M. Proc. natn. Acad. Sci. U.S.A. 80, 6917–6921 (1983).
Rimm, D. L., Horness, D., Kucera, J. & Blattner, F. R. Gene 12, 301–309 (1983).
Bolivar, F. et al. Gene 2, 95–113 (1977).
Messing, J. & Viera, J. Gene 19, 269–276 (1982).
Sanger, F., Coulson, A. R., Barell, B. G., Smith, A. J. H. & Roe, B. A. J. molec. Biol. 143, 161–178 (1980).
Messing, J., Crea, R. & Seeburg, P. H. Nucleic Acids Res. 9, 309–321 (1982).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Collins, M., Rubin, G. Structure of chromosomal rearrangements induced by the FB transposable element in Drosophila. Nature 308, 323–327 (1984). https://doi.org/10.1038/308323a0
Received:
Accepted:
Issue Date:
DOI: https://doi.org/10.1038/308323a0
- Springer Nature Limited
This article is cited by
-
DNA transposons mediate duplications via transposition-independent and -dependent mechanisms in metazoans
Nature Communications (2021)
-
Proteomics informed by transcriptomics for characterising active transposable elements and genome annotation in Aedes aegypti
BMC Genomics (2017)
-
FB elements can promote exon shuffling: a promoter-less white allele can be reactivated by FB mediated transposition in Drosophila melanogaster
Molecular Genetics and Genomics (2004)
-
Cytogenetic characteristics of a population of Chironomus riparius Meigen 1804 (Diptera, Chironomidae) from a polluted Po river station
Genetica (1996)
-
Genetic and molecular analysis of a set of unstable white mutants in Drosophila melanogaster
Genetica (1996)