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Function of a tRNA gene promoter depends on nucleosome position

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Abstract

We have used an in vitro procedure to direct nucleosomes to different sites on a chicken embryo tRNA gene. The results show that transcription of the tRNA gene depends on nucleosome position and in a functional promoter structure, the constant gene sequence TTCGA coincides with the nucleosome middle axis.

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Authors and Affiliations

  1. Institut für Molekularbiologie und Biochemie, Freie Universität Berlin, Arnimallee 22, 1000, Berlin, 33, FRG

    Stephanie Wittig & Burghardt Wittig

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  1. Stephanie Wittig
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  2. Burghardt Wittig
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Wittig, S., Wittig, B. Function of a tRNA gene promoter depends on nucleosome position. Nature 297, 31–38 (1982). https://doi.org/10.1038/297031a0

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  • DOI: https://doi.org/10.1038/297031a0

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