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Immunocytochemical localization of glutamic acid decarboxylase in monkey striate cortex

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Abstract

Neuronal cell bodies and synaptic terminals positive for glutamic acid decarboxylase, the enzyme responsible for synthesizing γ-amino butyric acid, have been located by immunocytochemical staining in all layers of the macaque monkey cortex. In layers II and III the staining pattern of periodic dots is identical with that seen in sections stained for cytochrome oxidase. The rows of dots run parallel with the ocular dominance columns, suggesting that the labelled neurones are preferentially related to each eye.

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Authors and Affiliations

  1. Department of Ophthalmology, University of Washington, Seattle, Washington, 98195, USA

    Anita E. Hendrickson

  2. MRC Neurochemical Pharmacology Unit, Cambridge, CB2 2QH, UK

    S. P. Hunt

  3. Department of Cell Biology, Baylor College of Medicine, Houston, Texas, 77030, USA

    J.-Y. Wu

Authors
  1. Anita E. Hendrickson
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  2. S. P. Hunt
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  3. J.-Y. Wu
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Hendrickson, A., Hunt, S. & Wu, JY. Immunocytochemical localization of glutamic acid decarboxylase in monkey striate cortex. Nature 292, 605–607 (1981). https://doi.org/10.1038/292605a0

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  • DOI: https://doi.org/10.1038/292605a0

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