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Three-dimensional structure of Escherichia coli initiator tRNAfMet

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Abstract

The crystal structure of Escherichia coli tRNAfMet an initiator transfer RNA, has been determined. While grossly similar to that of the chain-elongating yeast tRNAPhe, there are three major differences. One involves the folding of the anticodon loop; in particular, the position of the constant uridine, U33. This difference was unexpected and may be of functional significance

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Authors and Affiliations

  1. Department of Biology, Massachusetts Institute of Technology, Cambridge, MA, 02139

    Nancy H. Woo & Alexander Rich

  2. Department of Chemistry, Kent State University, Kent, Ohio, 44240

    Bruce A. Roe

Authors
  1. Nancy H. Woo
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  2. Bruce A. Roe
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  3. Alexander Rich
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Woo, N., Roe, B. & Rich, A. Three-dimensional structure of Escherichia coli initiator tRNAfMet. Nature 286, 346–351 (1980). https://doi.org/10.1038/286346a0

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  • DOI: https://doi.org/10.1038/286346a0

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