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Interactions between the carbohydrate chains of hyaluronate and chondroitin sulphate

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Abstract

Hyaluronic acid-derivatised beads spontaneously agglutinate with chondroitin sulphate-derivatised beads although neither bead type shows any self-agglutination. The interaction between hyaluronate and chondroitin sulphate is specific for these two glycosaminoglycans and appears to occur between their carbohydrate chains.

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References

  1. Lindahl, U. & Höök, M. A. Rev. Biochem. 47, 385–417 (1978).

    Article  CAS  Google Scholar 

  2. Sharon, N. Complex Carbohydrates (Addison-Wesley, New York, 1975).

    Google Scholar 

  3. Muir, H. & Hardingham, T. E. MTP Int. Rev. Sci., Biochem. Ser. 15, 153–222 (1975).

    Google Scholar 

  4. Balazs, E. A. (ed.) Chemistry and Molecular Biology of the Intercellular Matrix 3 (Academic, London, 1970).

  5. Underbill, L. & Dorfman, A. Expl cell. Res. 117, 155–164 (1978).

    Article  Google Scholar 

  6. Culp, L. A., Rollins, B. J., Buniel, J. & Hitri, S. J. Cell Biol. 79, 788–801 (1978).

    Article  CAS  Google Scholar 

  7. Bernfield, M. R., Cohn, R. H. & Bannerjee, S. D. Am. Zool. 13, 1067–1083 (1973).

    Article  CAS  Google Scholar 

  8. Toole, B. P. in Neuronal Recognition (ed. Barondes, S. H.) 275–342 (Plenum, London, 1976).

    Book  Google Scholar 

  9. Pintar, J. E. Devl Biol. 67, 444–464 (1978).

    Article  CAS  Google Scholar 

  10. Derby, M. A. Devl Biol. 66, 321–341 (1978).

    Article  ADS  CAS  Google Scholar 

  11. Pratt, M., Larsen, A. & Johnston, M. C. Devl Biol. 44, 298–305 (1975).

    Article  CAS  Google Scholar 

  12. Turley, E. A. & Roth, S. Cell 17, 109–115 (1979).

    Article  CAS  Google Scholar 

  13. Perkins, M. E., Ji, T. H. & Hynes, R. O. Cell 16, 941–952 (1979).

    Article  CAS  Google Scholar 

  14. Underbill, C. B. & Keller, J. M. J. cell. Physiol. 89, 53–64 (1976).

    Article  Google Scholar 

  15. Dubois, M., Gilles, K. A., Hamilton, J. K., Rebers, P. A. & Smith, F. Analyt. Chem. 28, 350–356 (1956).

    Article  CAS  Google Scholar 

  16. Lowry, O. H., Rosebrough, N. J., Farr, A. L. & Randall, R. J. J. biol Chem. 193, 265–275 (1951).

    CAS  PubMed  Google Scholar 

  17. Bradford, M. M. Analyt. Biochem. 72, 248–254 (1976).

    Article  CAS  Google Scholar 

  18. Murphy, J. B. & Kies, M. W. Biochim. biophys. Acta 45, 382–384 (1960).

    Article  CAS  Google Scholar 

  19. Kalckar, H. J. biol. Chem. 167, 461–486 (1947).

    CAS  PubMed  Google Scholar 

  20. Dische, Z., Shettles, L. B. & Osmos, M. Archs Biochem. Biophys. 22, 189–192 (1949).

    Google Scholar 

  21. Aspinail, G. O. & Ferrier, R. J. Chem. Ind. (Lond.), 1216 (1957).

  22. Heingarde, D. Biochim. biophys. Acta 285, 193–407 (1972).

    Article  Google Scholar 

  23. Brass, L. F. & Bensusan, H. B. Biochim. biophys. Acta 444, 43–52 (1976).

    Article  CAS  Google Scholar 

  24. Tolksdorf, S., McCready, M. H., McCullagh, D. R. & Schwenk, E. J. Lab. clin. Med. 34, 74–80 (1949).

    CAS  Google Scholar 

  25. Fransson, L. A. & Coster, L. Biochim. biophys. Acta 582, 132–144 (1979).

    Article  CAS  Google Scholar 

  26. Welti, D., Rees, D. A. & Welsh, E. J. Eur. J. Biochem. 94, 505–514 (1979).

    Article  CAS  Google Scholar 

  27. Winter, W. T., Smith, P. J. C. & Arnott, S. J. molec. Biol. 99, 219–235 (1975).

    Article  CAS  Google Scholar 

  28. Winter, W. T., Arnott, S., Isaac, D. H. & Atkins, E. D. T. J. molec. Biol. 125, 1–19 (1978).

    Article  CAS  Google Scholar 

  29. Hardingham, T. E. & Muir, H. Biochim. biophys. Acta 279, 401–405 (1972).

    Article  CAS  Google Scholar 

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Authors and Affiliations

  1. Department of Biology, Johns Hopkins University, Baltimore, Maryland, 21218

    E. A. Turley & S. Roth

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  1. E. A. Turley
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  2. S. Roth
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Turley, E., Roth, S. Interactions between the carbohydrate chains of hyaluronate and chondroitin sulphate. Nature 283, 268–271 (1980). https://doi.org/10.1038/283268a0

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  • DOI: https://doi.org/10.1038/283268a0

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