Skip to main content
SpringerLink
Log in

Effects of visual experience on the maturation of the efferent system to the corpus callosum

  • Letter
  • Published:

From Nature

View current issue Submit your manuscript

Abstract

IN normal adult cats the first and second visual areas (V1 and V2) in the two cerebral hemispheres are interconnected through the corpus callosum (CC) by neurones (callosal neurones) which have a characteristic laminar location and are restricted to the region of the boundary between cytoarchitectonic areas 17 (V1) and 18 (V2)1–4. Callosal neurones acquire this distribution postnatally by disappearing (dying, or eliminating their callosal connections) from most of areas 17 and 18 and decreasing in number in layer VI (refs 5, 6). Here we show that although kittens deprived of pattern vision by binocular lid suture still develop an apparently normal distribution of callosal neurones, monocularly deprived or enucleated, or bilaterally squinted kittens retain to adulthood some callosal neurones in parts of area 17 where such neurones are not normally found. Thus, visual experience can influence the selection of callosal neurones although this selection is probably influenced by more than one factor.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  1. Innocenti, G. M. & Fiore, L. Neurosci. Lett. 2, 245–252 (1976).

    Article  CAS  Google Scholar 

  2. Shatz, C. J. J. comp. Neurol. 173, 497–518 (1977).

    Article  CAS  Google Scholar 

  3. Sanides, D. & Donate-Oliver, F. in Architectonics of the Cerebral Cortex (eds Brazier, M. A. B. & Petsche, H.) 227–234 (Raven, New York, 1978).

    Google Scholar 

  4. Innocenti, G. M. (in preparation).

  5. Innocenti, G. M., Fiore, L. & Caminiti, R. Neurosci. Lett. 4, 237–242 (1977).

    Article  CAS  Google Scholar 

  6. Innocenti, G. M. Archs ital. Biol. 116, 463–470 (1978).

    CAS  Google Scholar 

  7. Hubel, D. H. & Wiesel, T. N. J. Neurophysiol 28, 1041–1059 (1965).

    Article  CAS  Google Scholar 

  8. Shatz, C. J. comp. Neurol. 171, 229–246 (1977).

    Article  CAS  Google Scholar 

  9. Wiesel, T. N. & Hubel, D. H. J. Neurophysiol. 28, 1029–1040 (1965).

    Article  CAS  Google Scholar 

  10. Hamburger, V. & Levi-Montalcini, R. J. exp. Zool. 111, 457–501 (1949).

    Article  CAS  Google Scholar 

  11. Redfern, P. A. J. Physiol., Lond. 209, 701–709 (1970).

    Article  CAS  Google Scholar 

  12. Clarke, P. G. H., Rogers, L. A. & Cowan, W. M. J. comp. Neurol. 167, 125–142 (1976).

    Article  CAS  Google Scholar 

  13. Rakic, P. Nature 261, 467–471 (1976).

    Article  ADS  CAS  Google Scholar 

  14. Hollyday, M. & Hamburger, V. J. comp. Neurol. 170, 311–320 (1976).

    Article  CAS  Google Scholar 

  15. Hubel, D. H., Wiesel, T. N. & Le Vay, S. Phil. Trans. R. Soc. B278, 377–409 (1977).

    Article  CAS  Google Scholar 

  16. Lund, R. D., Mitchell, D. E. & Henry, G. H. Brain Res. 144, 169–172 (1978).

    Article  CAS  Google Scholar 

  17. Choudhury, B. P., Whitteridge, D. & Wilson, M. E. Q. J. exp. Physiol. 50, 214–219 (1965).

    Article  CAS  Google Scholar 

  18. Berlucchi, G., Gazzaniga, M. S. & Rizzolatti, G. Archs ital. Biol. 105, 583–596 (1967).

    CAS  Google Scholar 

  19. Hubel, D. H. & Wiesel, T. N. J. Neurophysiol. 30, 1561–1573 (1967).

    Article  CAS  Google Scholar 

  20. Bilge, M., Bingle, A., Seneviratne, K. N. & Whitteridge, D. J. Physiol., Lond. 191, 116P (1967).

    CAS  PubMed  Google Scholar 

  21. Tusa, R. J., Palmer, L. A. & Rosenquist, A. C. J. comp. Neurol. 177, 213–236 (1978).

    Article  CAS  Google Scholar 

  22. Berlucchi, G. Brain Res. 37, 371–392 (1972).

    Article  CAS  Google Scholar 

  23. Doty, R. W. & Negrao, N. in Handbook of Sensory Physiology, Vol. 73 (ed. Jung, R.) 543–582, Springer, Berlin (1973).

    Google Scholar 

  24. Keating, M. J. Phil. Trans. R. Soc. Lond. B278, 277–294 (1977).

    Article  CAS  Google Scholar 

  25. Vakkur, G. J., Bishop, P. O. & Kozak, W. Vision Res. 3, 289–314 (1963).

    Article  Google Scholar 

  26. Glaser, E. M. & Van der Loos, H. IEEE Trans. biomed. Engng 12, 22–31 (1965).

    Article  CAS  Google Scholar 

  27. Coleman, D. R., Scalia, F. & Cabrales, E. Brain Res. 102, 156–163 (1976).

    Article  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Institute of Anatomy, University of Lausanne, Rue du Bugnon 9, CH–1011, Lausanne–CHUV, Switzerland

    G. M. INNOCENTI & D. O. FROST

Authors
  1. G. M. INNOCENTI
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. D. O. FROST
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

INNOCENTI, G., FROST, D. Effects of visual experience on the maturation of the efferent system to the corpus callosum. Nature 280, 231–234 (1979). https://doi.org/10.1038/280231a0

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1038/280231a0

  • Springer Nature Limited

This article is cited by

Search

Navigation