Abstract
The RNA polymerase mutation, alt-1, affects the σ subunit and alters the in vitro selectivity of RNA polymerase to parallel the in vivo phenotype. We propose that the mutation changes the distribution of functionally distinct polymerase isomers.
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Travers, A., Buckland, R., Goman, M. et al. A mutation affecting the σ subunit of RNA polymerase changes transcriptional specificity. Nature 273, 354–358 (1978). https://doi.org/10.1038/273354a0
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DOI: https://doi.org/10.1038/273354a0
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