Abstract
MURINE T lymphocytes that mediate the lysis of virus-infected cells show specificity both for the viral cell surface antigens and for the H–2K or D antigens of the major histo-compatibility complex1–8. The cytotoxic T lymphocytes and the target cell must share H–2K or D products. The experiments reported here demonstrate that there is a similar requirement for partial HLA identity between human cytotoxic lymphocytes and influenza virus-infected target cells.
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MCMICHAEL, A., TING, A., ZWEERINK, H. et al. HLA restriction of cell-mediated lysis of influenza virus-infected human cells. Nature 270, 524–526 (1977). https://doi.org/10.1038/270524a0
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DOI: https://doi.org/10.1038/270524a0
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