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2-Aminoadenine is an adenine substituting for a base in S-2L cyanophage DNA

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Abstract

THE properties of DNA from viruses acting on blue-green algae (cyanophages) have been studied in only a few instances1,2. It is not known whether these DNA molecules contain any unusual bases3–7 or some modified (methylated) bases known to be present in DNA of many prokaryotes and to be specific for host modification and restriction phenomena. Here we report the isolation and identification of the base 2-aminoadenine and its deoxyribonucleoside from S-2L cyanophage DNA. Some unusual properties of this DNA in which adenine is completely substituted with 2-aminoadenine are described.

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Authors and Affiliations

  1. A. N. Belozersky Laboratory of Molecular Biology and Bioorganic Chemistry, Lomonosov Moscow State University, Moscow and Biological Institute, Zhdanov Leningrad State University, Leningrad, USSR

    M. D. KIRNOS, I. Y. KHUDYAKOV, N. I. ALEXANDRUSHKINA & B. F. VANYUSHIN

Authors
  1. M. D. KIRNOS
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  2. I. Y. KHUDYAKOV
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  3. N. I. ALEXANDRUSHKINA
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  4. B. F. VANYUSHIN
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KIRNOS, M., KHUDYAKOV, I., ALEXANDRUSHKINA, N. et al. 2-Aminoadenine is an adenine substituting for a base in S-2L cyanophage DNA. Nature 270, 369–370 (1977). https://doi.org/10.1038/270369a0

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  • DOI: https://doi.org/10.1038/270369a0

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